Complement receptor mediates enhanced flavivirus replication in macrophages
نویسندگان
چکیده
Evidence is presented that M phi complement receptors (CR3) mediate IgM-dependent enhancement of flavivirus replication in the presence of complement. Enhancement is blocked by pretreatment of macrophages with monoclonal antibody Ml/70, which inhibits CR3 binding, but not by pretreatment with monoclonal antibody 2.4G2, which inhibits FcR binding.
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 158 شماره
صفحات -
تاریخ انتشار 1983